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Abstract
In order to assess the clinical, pathogenetic, functional variant of the course of peptic ulcer disease, I conducted a study of 112 patients with gastric ulcer (34), duodenal ulcer (78). The diagnosis was verified in accordance with the requirements of the modern standard, with an assessment of histomorphological secretory motor, hormonal disorders, as well as the degree of N. rulori contamination, eradication and its effectiveness. Psychosomatic status was assessed using complex methods: multilateral personality studies, the Hamilton scale for assessing depression, the Spielberg scale of situational and personal anxiety, the Beck depression scale, the "unfinished sentences" method for assessing violations in the relationship system.
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References
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- . V. Ivashkin, E. Baranovskaya, E. Stepanova, et al., "Peptic Ulcer Disease and Chronic Gastritis Associated with H. Pylori Infection: Respiratory Laser Diagnostics and Modern Therapy," Doctor, 2008.
- . I. V. Mayev, Y. A. Kucheryavy, D. N. Andreev, et al., "Eradication Therapy of Helicobacter Pylori Infection: A Review of Global Trends," Ther. Archive, 2014.
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- . S. I. Rapoport, Gastritis: Handbook for Doctors, Moscow, Russia: Medpraktika-M, 2010.
- . V. A. Isakov, "Epidemiology of GERD: East and West," Clin. Exp. Gastroenterol., 2004.
- . A. A. Svistunov, M. A. Osadchuk, E. D. Mironova, et al., "Role of the Main Risk Factors and Endocrine Cells of the Antrum Producing Motilin in Cholelithiasis," Ther. Archive, 2022.
- . T. V. Bakhristova and E. V. Drozdovskaya, "Analysis of Risk Factors for Gastrointestinal Diseases," in Topical Issues of Improving Medical Care for Professional Medical Education: Collection of Medical Materials, Belgorod, Russia, 2019.
- . L. N. Ivanov, M. L. Kolotilova, and A. V. Loseva, Gastritis and Peptic Ulcer Disease, Cheboksary, Russia: Publishing House of the Chuvash University, 2019.
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References
. K. I. Grigoriev, Therapeutic Care for Children with Diseases of the Digestive System.
. V. Ivashkin, E. Baranovskaya, E. Stepanova, et al., "Peptic Ulcer Disease and Chronic Gastritis Associated with H. Pylori Infection: Respiratory Laser Diagnostics and Modern Therapy," Doctor, 2008.
. I. V. Mayev, Y. A. Kucheryavy, D. N. Andreev, et al., "Eradication Therapy of Helicobacter Pylori Infection: A Review of Global Trends," Ther. Archive, 2014.
. V. T. Ivashkin, Ed., Recommendations for the Diagnosis and Treatment of Peptic Ulcer Disease: A Manual for Doctors. Moscow, Russia: 2005.
. Y. S. Zimmerman, "The Problem of Etiology and Pathogenesis of Peptic Ulcer Disease: Rereading V.H. Vasilenko," Klin. Med., 2011.
. Y. S. Zimmerman, "Peptic Ulcer Disease: Actual Problems of Etiology, Pathogenesis, and Differentiated Treatment," Klin. Med., 2012.
. M. P. Shimes and A. P. Nesterova, Peptic Ulcer of the Stomach and Duodenum, Moscow, Russia: State Publishing House of Medical Literature, 2012.
. Y. V. Vasiliev and I. V. Yashina, Etiopathogenesis of Peptic Ulcer Disease, Moscow, Russia: 2001.
. I. N. Agaev, N. A. Veliev, and I. S. Malkov, "Cicatricial Deformity of the Duodenum in Surgery of Peptic Ulcer," Kazan Med. J., 2003.
. V. H. Vasilenko, A. L. Grebenev, and A. A. Sheptulin, Peptic Ulcer: Modern Concepts of Pathogenesis, Diagnosis, and Treatment, Moscow, Russia: Medicine, 1987.
. A. E. Lychkova, "Features of the Motor Activity of the Stomach in Gastroesophageal Reflux Disease," in 7th Congress of the Scientific Society of Gastroenterologists of Russia: Abstracts of Reports, Exp. Clin. Gastroenterol., Moscow, Russia, 2007.
. V. T. Ivashkin and V. A. Isakov, "The Main Provisions of the II Maastricht Agreement: Recommendations for Treating H. Pylori-Associated Diseases in Russia," Russ. J. Gastroenterol. Hepatol. Coloproctol., 2001.
. A. B. Zhebrun, V. A. Alexandrova, L. B. Goncharova, and E. I. Tkachenko, Diagnosis, Prevention, and Treatment of H. Pylori-Associated Diseases: Handbook for Doctors, St. Petersburg, Russia: 2002.
. E. M. Delaney, S. Wilson, A. Roalfe, et al., "Randomized Controlled Trial of H. Pylori Testing and Endoscopy for Dyspepsia in Primary Care," BMJ, 2001.
. M. B. Shcherbinina, O. I. Khasilev, V. E. Kudryavtseva, and I. Ya. Budzak, "Modern Directions of Noninvasive Diagnosis of Stomach Diseases," Suchasna Gastroenterology, 2004.
. Recommendations for the Diagnosis and Treatment of H. Pylori Infection in Adults with Peptic Ulcer of the Stomach and Duodenum, Russ. J. Gastroenterol. Hepatol. Coloproctol., 1998.
. E. S. Ryss and E. E. Zvartau, Pharmacotherapy of Peptic Ulcer, St. Petersburg, Russia: 1998.
. S. M. Tkach, "XI United European Gastroenterological Week," Suchasna Gastroenterology, Kiev, Ukraine, 2003.
. L. V. Kudryavtseva and V. A. Isakov, "H. Pylori Resistance to Amoxicillin, Clarithromycin, and Metronidazole in Russia and Its Clinical Significance," in Diagnosis and Treatment of Diseases Associated with H. Pylori, 1999.
. S. A. Palevskaya and A. G. Korotkevich, Endoscopy of the Gastrointestinal Tract, 2nd ed., Moscow, Russia: GEOTAR-Media, 2020.
. I. V. Mayev, A. A. Samsonov, and D. N. Andreev, Infection of Helicobacter Pylori, Moscow, Russia: GEOTAR-Media, 2017.
. "Consultant Plus," [Online]. Available: https://kurskmed.com/department/library/page/Consultant_Plus.
. "World Health Organization," [Online]. Available: https://www.who.int/ru/.
. "CyberLeninka Scientific Electronic Library," [Online]. Available: https://cyberleninka.ru/.
. I. N. Agaev, N. A. Veliev, and I. S. Malkov, "Cicatricial Deformity of the Duodenum in Surgery of Peptic Ulcer Disease," Kazan Med. J., 2003.
. V. V. Benedict, T. V. Shashkova, I. P. Kryvyi, and S. N. Krysa, "The Importance of X-Ray and Endoscopic Studies of the Stomach in Comprehensive Examination of Patients after Resections and Vagotomies," Ther. Archive, 1993.
. A. M. Lassen, F. M. Pedersen, P. Bytzer, et al., "H. Pylori `Test and Eradicate' or Prompt Endoscopy for Management of Dyspeptic Patients: A Randomized Controlled Trial with One-Year Follow-Up," Lancet, 2000.
. N. B. Gubergrits and I. N. Ostroukhova, "Severity of H. Pylori Infection in Patients with Chronic Pancreatitis," Russ. J. Gastroenterol. Hepatol. Coloproctol., 2002.
. A. A. Sheptulin, T. L. Lapina, et al., Diagnosis and Treatment of Functional Dyspepsia, Moscow, Russia: Russian Gastroenterological Association, 2011.
. S. I. Rapoport, Gastritis: Handbook for Doctors, Moscow, Russia: Medpraktika-M, 2010.
. V. A. Isakov, "Epidemiology of GERD: East and West," Clin. Exp. Gastroenterol., 2004.
. A. A. Svistunov, M. A. Osadchuk, E. D. Mironova, et al., "Role of the Main Risk Factors and Endocrine Cells of the Antrum Producing Motilin in Cholelithiasis," Ther. Archive, 2022.
. T. V. Bakhristova and E. V. Drozdovskaya, "Analysis of Risk Factors for Gastrointestinal Diseases," in Topical Issues of Improving Medical Care for Professional Medical Education: Collection of Medical Materials, Belgorod, Russia, 2019.
. L. N. Ivanov, M. L. Kolotilova, and A. V. Loseva, Gastritis and Peptic Ulcer Disease, Cheboksary, Russia: Publishing House of the Chuvash University, 2019.
. E. V. Ferubko, T. D. Rendyuk, K. A. Pupykina, et al., Herbal Medicines for the Prevention and Treatment of Digestive System Diseases, Moscow, Russia: Sam Polygraphist, 2020.
. A. V. Nesterenko, "Influence of Risk Factors on the Development of Gastrointestinal Diseases," in Problems and Prospects of Scientific Research: Materials of the XXII Scientific and Practical Conference, Krasnodar, Russia, 2019.